17 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... and gut, which causes ... #clincial #peds ... #adrenal #calcifications ... #infant #NEJM #
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Investigations: full blood ... osmolarity If cause ... investigations depending on clinical ... context and signs ... screen, including blood
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... hypertension (blood ... 109 mm Hg) with clinical ... bruit or signs ... hypertension (blood
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Abdominal pain (20%) Renal ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... 21-OHD in the adrenal ... Signs/Symptoms/Complications ... endocrinology #peds
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... auricular papules Clinical ... onset [33-74%] • Blood
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Pathogenesis and clinical ... artery Backup of blood ... retroperitoneal masses ... Obstruction of blood ... Pathophysiology #Signs
Radial Head Elbow Fracture with displaced Fat Pads
Intra-Articular Fracture of the Elbow with displaced fat pads
displaced Fat Pads ... So even in a case ... considerable amount of blood ... called the “Sail sign ... Fracture #trauma #clinical
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal ... anaphylaxis, toxins/meds ... O2 delivery • PE ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal ... anaphylaxis, toxins/meds ... O2 delivery • PE ... #differential #causes