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oncology hematology management differential erythematosus lupus systemic vasculitis anemia aplastic autoimmune chronic classification cll dermatology emergencies encephalopathy hemeonc lymphocytic mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Lymphocytosis: Absolute blood ... • Sezary syndrome ... #diagnosis #workup
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... cutis Diagnosis ... neutrophils in the blood
SOAP BRAIN MD Mnemonic for Systemic Lupus Erythematosus (SLE) S - Serositis (Pleuritis, Pericarditis) O - Oral Ulcers A
Photosensitivity B - Blood ... Pancytopenia) R - Renal ... Neuropsychiatric Symptoms ... #Rheumatology # ... Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Out Secondary Causes ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... • Improve the symptoms ... result from low blood ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Hypertensive emergency, Blood ... Neurological symptoms ... elevated white blood ... the underlying cause ... until cause identified
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #rheumatology #
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