12 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
of both adrenal ... and gut, which causes ... #clincial #peds ... #adrenal #calcifications ... #infant #NEJM #
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Undifferentiated Shock ... ), RV Failure (PE ... Toxins (CCB, BB, BRASH ... Failure, Endocrine (adrenal ... albumin, trauma), Renal
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... tamponade, Vascular → PE ... findings based on cause ... infusion reactions, adrenal ... uw_IMresidency #Shock
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal ... anaphylaxis, toxins/meds ... vomiting/diarrhea), renal ... O2 delivery • PE ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal ... anaphylaxis, toxins/meds ... vomiting/diarrhea), renal ... O2 delivery • PE ... #differential #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& hemorrhagic rash ... ; symptoms of shock ... Vesicular & pruritic rash ... > Inflammation causes ... #Immunization #peds
Extrapulmonary manifestations of COVID-19
 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke
 • Renal:
Anosmia, Stroke • Renal ... Gastrointestinal: Diarrhea, Nausea ... arrhythmias, Cardiogenic shock ... , Erythematous rash
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
maculopapular rash ... • Others: nausea ... Weil's disease (renal ... hemorrhage • ARDS • Shock
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... 21-OHD in the adrenal ... as "congenital adrenal ... vomiting • Late (shock ... endocrinology #peds
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Infections BRASH ... Bradycardia • Renal ... blocking agent • Shock ... Spondylarthropathies Other causes ... differential #diagnosis #causes