31 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Clinical Manifestations ... and Management ... #Hematology #SickleCell
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rheumatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... , hypotension, rash ... immunosuppressive meds ... #cellulitis #dermatology ... #legs #clinical
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #Summary #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... auricular papules Clinical ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... Chronic Management ... Avoid meds that ... #treatment #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology