9 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
studies show that PRBC ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology ... VisualAbstract #Trials #PRBC
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... disease: > 2 • NASH ... • Bilirubin: RBC ... • LDH: Heart, RBC
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Parvovirus B19 - EBV ... Pancytopenia: • ↓ RBC ... Anemia #oncology #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study
NEJM 2018 https ... out what does cause ... TessaRDavis #EBM ... VisualAbstract #Peds ... Infusion #Rates #NEJM
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... amyloidosis Causes ... acute HIV, HBV, EBV ... autoimmune hepatitis, PBC ... gastric tumors • Hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Symptoms: • Gottron rash ... • ANA < 20 % IBM ... statins - probably caused ... Other Diseases: • PBC