7 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... lesions Abdominal pain
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... is the main clinical ... Petechial or purpuric rash ... ) • Heart, lung ... SJIA], systemic lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... : • Joint pain ... : • Symptoms limited ... to: Arthritis, Fever ... Chronic B-cell activation
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... malaise) - Muscle pain ... Inflammation and pain ... - Lupus - Leukemia
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... General: fever, ... , cough, chest pain ... skin (16-32%): lupus ... : ACUTE, fever,
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
substantial muscle pain ... : • Gottron rash ... : • Muscle pain ... : Fever, joint pain ... : • Fever • Interstitial