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diagnosis rheumatology differential erythematosus lupus management signs sle vasculitis autoimmune classification dermatology macrophage mas myopathy myositis oncology sarcoidosis sweet vasculitides
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... is the main clinical ... Petechial or purpuric rash ... ) • Heart, lung ... #Management #Hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... lesions Abdominal pain
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... malaise) - Muscle pain ... Inflammation and pain ... , breast CA - Hematologic
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... the lymphatic system ... General: fever, ... 5-10%, nervous system ... : ACUTE, fever,
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... : • Joint pain ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... Chronic B-cell activation
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... mucositis - Rash ... Symptoms (Sx) in ... Vasculitis: • Fevers ... , testes -> pain
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... Vasculitis: • Fevers ... , mucositis • Rash ... • Progressive symptoms ... involvement, abdominal pain
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
substantial muscle pain ... : • Gottron rash ... : Fever, joint pain ... : • Fever • Interstitial ... • Conduction system
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