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diagnosis differential rheumatology systemic signs vasculitis activation arthropathies arthropathy autoantibodies causes classification disorders hematology infections infectiousdiseases joint macrophage management mas
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fever (50%), Depression ... effusion, Restrictive lung ... Demyelinating syndromes ... #erythematosus # ... signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... rash • Erythematous ... : • Symptoms limited ... to: Arthritis, Fever
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... Erythematosus ( ... SLE), should have ... other symptoms ... like “butterfly rash
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... papules, pustules, erythematous ... of a "flu-like syndrome ... Constitutional symptoms ... #AIDS #pulmonary
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Petechial or purpuric rash ... ) • Heart, lung ... erythematosus [ ... SLE], AOSD) • Infection
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Herpes Viruses (HSV ... Disease - Systemic Lupus ... Erythematosus ... (bulbar symptoms ... - small cell lung
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... erythematosus, ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... Cryoglobulins • HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Progressive symptoms
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