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diagnosis differential rheumatology erythematosus pulmonary systemic infectiousdiseases management signs vasculitis activation acute amiodarone arthropathies arthropathy autoantibodies autoimmune bronchiectasis cardiology classification
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fever (50%), Depression ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs #symptoms
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... (45%) • Fever ... (28%) • Skin rash ... • New onset SLE
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... Other auto-immune, Infectious ... autoantibodies #signs #symptoms
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 syndromes ... Constitutional symptoms ... #Infections #HIV ... #AIDS #pulmonary
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... fibromyalgia) • Infections ... : • Symptoms limited ... to: Arthritis, Fever
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... within 1 month of infection ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... ) • Heart, lung ... SJIA], systemic lupus ... erythematosus [SLE ... ], AOSD) • Infection
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... in the adjacent lung ... of the affected lung ... , CCP, ANCA • HIV
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... to exclude are infections ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... Cryoglobulins • HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... Vasculitis: • Fevers ... , mucositis • Rash ... • Progressive symptoms
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