7 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... Glomerulonephritis Myositis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Transverse myelitis ... , HIV, CMV, HTLV ... Behcet disease - SLE ... MCTD, Sjogren syndrome ... differential #algorithm
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... • Transverse Myelitis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... and leukemia • Lung
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... : • Gottron rash ... : Fever, joint pain ... weakness + atrophy- Hip ... : • Fever • Interstitial
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Rash, arthritis ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... vasculitis, and SLE ... Cryoglobulins • HIV
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... Conjunctivitis, mucositis ... • Rash, arthritis ... • Progressive symptoms
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
, verrucous) - Lung ... • Autoimmune (SLE ... night sweats, fever ... Cholesterol emboli syndrome ... Differential #Diagnosis #cardiology