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diagnosis differential erythematosus lupus systemic infectiousdiseases management pulmonary signs vasculitis activation acute aids autoantibodies autoimmune bronchiectasis cardiology classification endocarditis hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... #diagnosis #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
in HIV - Differential ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... (45%) • Fever ... (28%) • Skin rash ... • New onset SLE
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs #symptoms ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... Petechial or purpuric rash ... ) • Heart, lung ... erythematosus [SLE ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... in the adjacent lung ... of the affected lung ... , CCP, ANCA • HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... , mucositis • Rash ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... • Autoimmune (SLE ... night sweats, fever ... Cholesterol emboli syndrome ... Persistent bacteremia/fevers
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