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diagnosis differential rheumatology erythematosus signs management vasculitis activation acute arthropathies arthropathy autoantibodies autoimmune cardiology causes classification disorders endocarditis hematology infectiousdiseases
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... : Fever (50%), Depression ... effusion, Restrictive lung ... Demyelinating syndromes ... #SLE #systemic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... #Systemic #Lupus
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... (SLE), should have ... other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... : • Symptoms limited ... to: Arthritis, Fever ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Petechial or purpuric rash ... ) • Heart, lung ... lupus erythematosus ... [SLE], AOSD) •
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Herpes Viruses (HSV ... Behcet Disease - Systemic ... Lupus Erythematosus ... (bulbar symptoms ... - small cell lung
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... (45%) • Fever ... (28%) • Skin rash ... Central nervous system ... • New onset SLE
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... the lymphatic system ... General: fever, ... skin (16-32%): lupus ... 5-10%, nervous system
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... Vasculitis: • Fevers ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... Vasculitis: • Fevers ... , mucositis • Rash ... • Progressive symptoms
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