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diagnosis rheumatology differential erythematosus management systemic vasculitis activation arthropathies arthropathy autoimmune classification dermatology disorders hematology macrophage monoarthritis monoarticular msk myopathy
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fever (50%), Depression ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... : • Joint pain ... : • Symptoms limited ... to: Arthritis, Fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Petechial or purpuric rash ... ) • Heart, lung ... SJIA], systemic lupus ... erythematosus [SLE
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... inflammation of the joints ... and pain of the joints ... - Lupus - Leukemia
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... mucositis - Rash ... systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
SLE, atherosclerotic ... Presentation: Systemic Symptoms ... , mucositis • Rash ... • Progressive symptoms ... Palpable purpura, joint
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... : Fever, weight ... ear • Skin • Joints ... such as: • SLE
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
: • Gottron rash ... : Fever, joint pain ... • Misdiagnosed as ... but asymmetry may ... : • Fever • Interstitial
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