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diagnosis rheumatology erythematosus lupus systemic infections infectiousdiseases pulmonary vasculitis aids autoantibodies autoimmune bronchiectasis cardiology classification hiv infective intermittent marantic mimickers
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... Brucellosis • Liver or lung ... #Patterns #Differential
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... conditions: Autoimmune (SLE ... in up to 30% of cases ... #comparison #infective
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
in HIV - Differential ... Pneumonia: • 3 syndromes ... • CT: Halo sign ... of a "flu-like syndrome ... Constitutional symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... • Libman-Sacks endocarditis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... Bronchiectasis #pulmonary #differential
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... , verrucous) - Lung ... • Autoimmune (SLE ... Cholesterol emboli syndrome ... #Differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms
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