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diagnosis differential rheumatology lupus systemic pulmonary vasculitis autoantibodies autoimmune bronchiectasis classification infections infectiousdiseases mimickers myopathy myositis vasculitides
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... rash • Erythematous ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... • CT: Halo sign ... papules, pustules, erythematous ... Constitutional symptoms ... #AIDS #pulmonary
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... purpura: strong sign ... vasculitis, and SLE
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... , CCP, ANCA • HIV
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Progressive symptoms
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... : • Fever • Interstitial
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