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diagnosis rheumatology erythematosus lupus systemic infections pulmonary vasculitis aids arthropathies arthropathy autoantibodies autoimmune bronchiectasis classification disorders endocarditis headache hiv infectiousdiseases
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... Brucellosis • Liver or lung ... #Patterns #Differential
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... , fever, myalgia ... lesion • CNS infection
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... within 1 month of infection ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
in HIV - Differential ... Pneumonia: • 3 syndromes ... • CT: Halo sign ... of a "flu-like syndrome ... Constitutional symptoms
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... conditions: Autoimmune (SLE ... in up to 30% of cases ... #Endocarditis #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... permanent alopecia Differential ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... Nasal polyps and signs ... in the adjacent lung ... Bronchiectasis #pulmonary #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... , recent viral infection
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