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diagnosis rheumatology differential cardiology erythematosus infectiousdiseases lupus systemic classification conditions extrarticular febrile infective joint management marantic nbte noninfective pain rash
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... effusion, Restrictive lung ... Demyelinating syndromes
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... • Interstitial lung ... • Shrinking lung ... syndrome - SLE ... Lyme disease, Vasculitis
ID Approach to Fever and Rash - Diagnostic Algorithm Central Maculopapular (most common): Measles, Parvovirus 819 / EBV,
and Rash - Diagnostic ... Algorithm Central ... Mycoplasma), Infective endocarditis ... Parvovirus B19 (PPGSS), Vasculitis ... angiomatosis, Sweet syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... • Libman-Sacks endocarditis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... conditions: Autoimmune (SLE ... Clinical features: Fever ... in up to 30% of cases ... #comparison #infective
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... mucositis - Rash ... Presentation - Systemic Symptoms ... : • Fevers • ... , and SLE) • Urinalysis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... • Autoimmune (SLE ... night sweats, fever ... valvular disease • Vasculitis ... Persistent bacteremia/fevers
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... : • Fevers • Fatigue ... , mucositis • Rash ... • Progressive symptoms
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... • Autoimmune (SLE ... night sweats, fever ... valvular disease • Vasculitis ... Cholesterol emboli syndrome
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