7 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy (AFLP) ... Three syndromes ... child * Severe cases ... #AFLP #obstetrics ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... child * Severe cases ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Syndrome (Hemolysis ... of Pregnancy (AFLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #AFLP
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... Preeclampsia, HELLP ... Pregnancy #hepatology ... #obstetrics #obgyn
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
biliary obstruction, HELLP ... Syndrome, Celiac ... Toxic: Medication, Pregnancy ... #Acute #algorithm ... #hepatology