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hematology dermatology lupus sle dermatomyositis differential erythematosus product reactions signs symptoms systemic treatment vasculitis activation adultonset anemia antimda5 antimda5dm antinxp2
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... #management #treatment ... #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... onset [33-74%] • Blood ... #dermatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... mucositis - Rash ... pulses, bruis, or blood ... Large Vessel: Blood ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... pulses, bruits, or blood ... , mucositis • Rash ... #Rheumatology
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