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diagnosis differential hematology management causes erythematosus product reactions signs symptoms systemic activation algorithm autoantibodies classification disorders druginduced joint macrophage mas
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... symptoms #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Neurological 12% - Thrombocytopenia ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... : • Palpable Rash ... • Non-Palpable Rash ... : • Palpable Rash ... • Non-Palpable Rash
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... plateletcount), peripheral blood ... PLT in selected cases ... test, ANA (e.g., SLE ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology ... #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Reduced RBC • Washed ... maculopapular rash ... purpura & severe thrombocytopenia ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... Large Vessel: Blood ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... maculopapular rash ... purpura & severe thrombocytopenia ... diagnosis #management #hematology
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