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diagnosis management sle disease erythematosus stills adultonset aosd autoimmune clinical clues cutaneous dermatology differential druginduced hematology larva macrophage migrans myopathy
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... arthritis (sJIA) • Adult-onset ... lupus erythematosus ... Petechial or purpuric rash ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... solid cancers • Systemic ... Complications: MAS ... management #treatment #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... when infection has ... diagnosis #sle #clues #system ... erythematosus #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Disease Systemic ... with urticarial rash ... Rash: • Nonpruritic ... maculopapular skin rash ... AOSD #diagnosis #rheumatology
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
larva migrans skin Rash ... now with creepy rash ... migrating serpiginous rash ... Adult hookworms ... are first-line systemic
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... cancer-associated adult ... Symptoms: • Gottron rash ... • Conduction system ... Myositis #Myopathy #rheumatology
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