15 results
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... hemolytic transfusion reactions ... #Hemolysis #Classification ... #Algorithm
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... to complement activation ... types #allergy #table ... #classification
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... sequestration and activation ... without other cause ... diagnosis #comparison #table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Allergy #Diagnosis #Reactions ... #Table
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... Allergic reaction ... because T-Cell activation ... Allergy #Immunology #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... an immune reaction ... exposure to allergen causes ... because T-Cell activation ... #Types #Classification
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes - THE ALGORITHMIC ... macule and papule (Table ... either a drug reaction ... pathognomonic for SJS or EM ... Maculopapular #Rash #Algorithm
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
serious adverse reaction ... The exact cause ... antibodies which cause ... platelet activation ... thrombocytopenia #COVID #pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... Pathophysiology: ... sympathetic + ADH activation ... Exclude other AKI causes ... Classification:
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology