9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... #management #criticalcare
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Classification ... #management #cold
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Type 1 - Mediators ... cell antigens, leading ... to complement activation ... allergy #table #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Life-threatening organ dysfunction ... cytokines, complement activation ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT ... #Diagnosis #Management
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... immune reaction, leading ... because T-Cell activation ... #Classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... by uncontrolled activation ... Types of HLH • ... MAS-HLH: Macrophage Activation ... uncontrolled immune activation
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... mild cognitive dysfunction ... Chronic B-cell activation