12 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Type 1 - Mediators ... antigens, leading ... to complement activation ... allergy #table #classification
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... #management #criticalcare
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Classification ... #management #cold
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... differential #causes #classification
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... differential #causes #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... immune reaction, leading ... activation takes ... #Classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... risk death), T-cell ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT ... #Diagnosis #Management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... complement • Classification ... IGG4 #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... Types of HLH • ... Approach • Initial management