9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... cellular antigen, leading ... #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... causes development ... because T-Cell activation ... ivy) #TypeIV #Type4 ... #Immunology #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... causes development ... because T-Cell activation ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... cell antigens, leading ... to complement activation ... #allergy #table ... #classification
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... #Shock #Types #Pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
gets activated leading ... by endothelial activation ... Exposure of Type-IV ... antibodies which can cause ... Rheumatic #Fever #Pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... Pathophysiology: ... Exclude other AKI causes ... Classification: ... HRS-AKI (formerly Type
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
channels open leading ... Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Types of HLH • ... Pathophysiology