8 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... of allergen-specific ... Allergic reaction ... because T-Cell activation ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... causes development ... because T-Cell activation ... #Types #Classification
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... : CLASS 1 - Sodium ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... to complement activation ... reactions #types #allergy ... #table #classification
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... : CLASS 1 - Sodium ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... sympathetic + ADH activation ... Exclude other AKI causes ... Classification: ... essential in all cases