1849 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... : • Cytokine Release ... • Cathepsin G release ... More common in severe ... overload, PCC to reverse
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
digoxin, consider reversal ... diagnosis #management #pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... activation and PF4 release ... • Serotonin Release ... including flushes), reverse
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
virus that uses reverse ... #oncogenesis #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Glutamate reverse ... inhibitor of glutamate release-reduces
Corticosteroids - effects and side effects

#Corticosteroids #Pharmacology #Pathophysiology #SideEffects #Adverse #Mechanism
#Pharmacology #Pathophysiology ... #SideEffects #Adverse
Pathophysiology of Severe Chronic Mitral Regurgitation

#Mitral #Regurgitation #Pathophysiology #Cardiology
Pathophysiology ... of Severe Chronic ... Regurgitation #Pathophysiology
Aortic Regurgitation - Pathophysiology
 • Early Mild Aortic Regurgitation
 • Chronic Severe Aortic Regurgitation
 • Decompensated
Regurgitation - Pathophysiology ... Regurgitation • Chronic Severe ... Regurgitation • Acute Severe ... Regurgitation #Pathophysiology
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
deficiency or severe ... insensitivity #DKA #Pathophysiology
Hypothalamic releasing hormones and the pituitary trophic hormones. 

#Hypothalamic #Pituitary #Hormones #Release #Trophic #Anterior #Hypothalamus #Endocrinology
Pituitary #Hormones #Release ... Endocrinology #Pathophysiology