22 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
hyperplasia of bone ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... candidate) - Bone ... #Diagnosis #Causes ... #Workup #hematology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... values supporting hematologic ... Bone marrow biopsy ... #diagnosis
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Aortitis - Diagnosis ... History: - Fever ... hypertension) - Symptoms ... Nivolumab, GM-CSF ... #Workup #Differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... • Liver (80%) ... Intestine - Other causes ... #hepatology
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
Diagnosis Framework ... Pneumonia • CHF ... effusion/Tamponade Hematologic ... : • Anemia ... • Temperature/FEVER
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
be used by the bone ... is made in the liver ... Hematologic Malignancy ... Sideroblastic anemia ... #Diagnosis #Causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... - Hemolytic anemia ... deficiency • Liver ... mountain spotted fever ... #Diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... • Pernicious anemia ... mineralization Symptoms ... Phosphatase: • Other causes