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hematology neurology differential hemeonc hemophagocytic hlh leukemia lymphohistiocytosis mds myelodysplastic syndromes anemia aplastic apml barre bells bowel chronic classification cll
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Bone marrow ... #Management #treatment ... #hematology #oncology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... Treatment: • Global ... Gastroenterology and Hepatology ... #Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... sepsis), PE, DAH, CHF ... #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... changes, stroke symptoms ... #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... microglobulin Treatment ... Warm AIHA • Bone ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Transplantation including bone ... Neurological symptoms ... the underlying cause ... • Treatment of ... #diagnosis #management
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... 3 questions to work ... demyelination syndrome ... include vaptans (HF ... #Treatment #management
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