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Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
and first-level screening ... test - High sensitivity ... and specificity ... #Diagnosis #Workup ... #Table
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
diseased by the screening ... Specificity is the ... scores on the screening ... #Specificity #PositivePredictiveValue ... #Calculation #Table
It's eye-opening to realize how many tests with reasonable-appearing sensitivity or specificity will end up being
reasonable-appearing sensitivity ... or specificity ... or sensitivity ... #Classification ... #Specificity #Graph
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... hypercalcemia rests ... value of 0.0115, sensitivity ... for correct classification ... ) was 0.80 and specificity
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
Colorectal Cancer Screening ... tests: • FIT: ... 94% specificity ... Cancer #colon #Screening ... #table #management
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
Colorectal Cancer Screening ... Colorectal Cancer Screening ... tests: • FIT: ... Cancer #colon #Screening ... #comparison #table
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - Algorithm ... Step 1) Screening ... have almost 100% specificity ... for AI (but low sensitivity ... Insufficiency #Algorithm
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... testing has higher specificity ... but lower sensitivity ... Screening Tests ... Screening Tests
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Disease - Diagnosis Algorithm ... IgA TTG has high sensitivity ... and specificity ... -A negative test ... gastroenterology #workup