56 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... Myopathies #Idiopathic #Myopathy ... #Comparison #Managment ... #algorithm #Rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... can present with rash ... including heliotrope rash ... anti-synthetase syndrome ... #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... load Drug-induced myopathy ... 5-15% of lupus myopathy ... #differential #diagnosis ... #comparison #rheumatology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
the ED with a rash ... the patient’s rash ... Scalded #Skin #Syndrome ... SSSS #Clinical #Photo ... Peds #Pediatrics #Dermatology
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Myopathies (IIM's) RASH ... antisynthetase syndrome ... Myopathies #IIMs #diagnosis ... dermatology #Myopathy ... #Rash
Yao Syndrome vs VEXAS

Zhuoer Xie, MD @ZhuoerXie

#Yao #Syndrome #VEXAS #diagnosis #comparison #rheumatology
Yao Syndrome vs ... ZhuoerXie #Yao #Syndrome ... #VEXAS #diagnosis ... #comparison #rheumatology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... , DRESS, Sweet syndrome ... SCVMCMed #Fever #Rash ... #dermatology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... - Differential diagnosis ... ChristmasTree #Rash ... rosea #clinical #dermatology ... #photo #PhysicalExam
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... MSAs #clinical #diagnosis ... #rheumatology #
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome ... Stevens #Johnsons #Syndrome ... Epidermal #Necrolysis #Comparison ... #Diagnosis #Dermatology