14 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... : 70 years old, ... ~10,000 new cases ... #Management #treatment ... #hematology #oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... Non-accidental Injury ... splenomegaly, abnormal neurology ... , back pain Haematology ... Peds #Pediatrics #Diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... may be normal in mild ... cases) • PT/INR ... Chronic Management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Ischemic Liver, IBD ... Vasculitis • Injury ... pathophysiology #hematology ... #differential #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... ↓Antithrombin Ill ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
pattern of liver injury ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... Necrosis) If mild ... #Management #Hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
typically present as mild ... hemolysis or liver injury ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Presentation: Injury ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... - Pleocytosis: Mild ... #management #neurology