29 results
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... osmolarity If cause ... investigations depending on clinical ... #nephrology #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical ... + myoglobin AKI ... #treatment #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... #rheumatology # ... cerebritis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical ... Treatment: • ... #summary #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... amphetamines) Toxic: • Radiologic ... Traumatic brain injury ... Anesthesia #Checklist #Diagnosis
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
: CLINICAL DIAGNOSIS ... exam and imaging Treatment ... Leflunomide (LEF) • JAKi ... Certolizumab, Golimumab), IL ... #management #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
the critically ill ... liver or renal injury ... perfusion - shock->treatments ... before beginning treatment ... gluconeogenesis Liver Injury
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
: • Based on clinical ... More likely to cause ... glucocorticoids - can cause ... - Improves clinical ... #management #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Discontinuation of causal ... comparison #table #rheumatology ... #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Mild LFT ↑ This ... Pediculus humanus, AKA ... Specific organ injury ... LBRF can be diagnosed ... microscopy #pathology #clinical