7 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Arthritis: • Joint ... pain • Swan neck ... Hodgkin lymphoma and leukemia
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, fever, joint pain ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... Inflammation and pain ... of the joints ( ... - Lupus - Leukemia ... #diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... vasculitis, and SLE ... differential #diagnosis #rheumatology