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diagnosis hematology differential rheumatology causes leukemia management oncology workup activation chronic cll criteria disease disorders erythematosus eularacr framework joint lymphocytic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... domain: Leukopenia, Thrombocytopenia ... #EULARACR #Classification ... #Criteria #SLE
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: • Vascular occlusion ... Drug induced - Bone ... Splenomegaly - CTD (SLE ... Associated - SLE ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... folate def - Bone ... - Autoimmune: SLE ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Disease Vaso-occlusive ... dz difficult to see ... Differentiate from vaso-occlusive ... diagnosis #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... test, ANA (e.g., SLE ... candidate) - Bone ... patients with thrombocytopenia ... Causes #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... infiltrates (anemia, thrombocytopenia ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... #Leukemia #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Neutropenia, anemia, thrombocytopenia ... Warm AIHA • Bone ... lymphoma • Marginal zone ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... reactions, and vaso-occlusive ... vasculitis, and SLE ... #rheumatology #classification
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
standing for: - Thrombocytopenia ... including systemic lupus ... erythematosus (SLE ... interfollicular zone ... #rheumatology #Thrombocytopenia
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