14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infiltrates (anemia, thrombocytopenia ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... /SLL into a significantly ... #Leukemia #Hematology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Proliferative Class Ill ... #Nephritis #SLE ... #Classification ... differential #diagnosis #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... domain: Leukopenia, Thrombocytopenia ... nephritis, Class Ill ... #EULARACR #Classification ... #Criteria #SLE
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Neutropenia, anemia, thrombocytopenia ... Warm AIHA • Bone ... lymphoma • Marginal zone ... workup #oncology #hematology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Pain in Sickle Cell ... Disease Vaso-occlusive ... dz difficult to see ... Differentiate from vaso-occlusive ... diagnosis #causes #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: • Vascular occlusion ... Drug induced - Bone ... Splenomegaly - CTD (SLE ... Associated - SLE ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... test, ANA (e.g., SLE ... candidate) - Bone ... not required in all ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Symptoms of anemia or thrombocytopenia ... - Progressive bore ... with anemia or thrombocytopenia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Syndrome #Diagnosis #Management