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hematology differential rheumatology oncology algorithm causes management leukemia activation anemia chronic cll criteria disease disorders erythematosus eularacr framework hemolytic hodgkins
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... domain: Leukopenia, Thrombocytopenia ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... test, ANA (e.g., SLE ... candidate) - Bone ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... folate def - Bone ... - Autoimmune: SLE ... #Framework #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : • Vascular occlusion ... Drug induced - Bone ... Splenomegaly - CTD (SLE ... Associated - SLE
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Disease Vaso-occlusive ... dz difficult to see ... Differentiate from vaso-occlusive ... #differential #diagnosis ... #causes #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Activation #Syndrome #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... genotypes): SS, SC, SE ... Schistocytes, thrombocytopenia ... #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Neutropenia, anemia, thrombocytopenia ... Warm AIHA • Bone ... #workup #oncology ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... hemostasis: - Thrombocytopenia ... Autoimmune Vasculitis (lupus ... deficiency Work ... Algorithm #Causes #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... infiltrates (anemia, thrombocytopenia ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
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