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diagnosis differential rheumatology hematology vasculitis clinical cryoglobulinemia cryoglobulins erythematosus high hyperkalemia leukemia manifestations monoclonal myelodysplastic nonpalpable palpable paraproteinemias potassium purpura
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... dermatomyositis, SLE ... Calmettes #Cutaneous ... differential #diagnosis #dermatology ... #oncology #clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... : • Acute cutaneous ... scarring • Subacute cutaneous ... inflammation Cutaneous
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: • Vascular occlusion ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... #nonpalpable #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... diagnosis #types #classification
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Causes: - Idiopathic ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... capillary leak syndrome ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... reactions, and vaso-occlusive ... vasculitis, and SLE ... #rheumatology #classification
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... reactions, and vaso-occlusive ... Strong sign of cutaneous ... tract, and often causes ... (lower legs), cutaneous
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... diseases: syßtemic lupus ... antiphospholipid syndrome ... High #Potassium #Classification ... #Causes
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