13 results
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs ... Diagnosis #dermatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... areas -> Scaring alopecia ... inflammation on skin ... pathophysiology #diagnosis #signs
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diffuse and Focal) Differential ... • Loose anagen syndrome ... - Secondary to Skin ... • Discoid lupus ... #dermatology #Differential
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... dermatomyositis, SLE ... #differential # ... diagnosis #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Secondary: CTD: SLE ... Disease • Cogan syndrome ... #dermatology #rheumatology ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Differential ... • Nonscarring alopecia
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #rashes #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... disease (SVC/IVC occlusion ... Behcet disease) Differential ... Oral aphthae : SLE ... diagnosis #management #signs
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... : • Vascular occlusion ... Kasabach-Merritt syndrome ... Associated - SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
aphthous ulcers, cutaneous ... such as systemic lupus ... reactions, and vaso-occlusive ... purpura: strong sign ... vasculitis, and SLE