11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #dermatology ... #joint #pain #skin
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus ( ... SLE), should have ... #arthropathy #arthropathies
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
erythematosus ... • Loose anagen syndrome ... - Secondary to Skin ... erythematosus ... #dermatology #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Arthritis: • Joint ... arthropathy • 90% joints
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... erythematosus, ... : Lupus erythematosus ... , Loose anagen syndrome ... Differential #Diagnosis #dermatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #Systemic #Lupus ... #Erythematosus ... #rheumatology #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: ... Sjögrens (15%) Skin ... Demyelinating syndromes ... #erythematosus #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... SJIA], systemic lupus ... erythematosus [ ... SLE], AOSD) • Infection ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... vesicular eruption - Joints ... erythematosus, ... reactions, and vaso-occlusive ... vasculitis, and SLE
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis ... myopathy #diagnosis #management