17 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #dermatology ... #joint #pain #skin
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
erythematosus ... • Loose anagen syndrome ... - Secondary to Skin ... erythematosus ... #dermatology #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Arthritis: • Joint ... arthropathy • 90% joints
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Localized / Focal ... erythematosus, ... : Lupus erythematosus ... , Loose anagen syndrome ... Differential #Diagnosis #dermatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... #erythematosus #
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Focal / Localized ... - Secondary to Skin ... • Discoid lupus ... erythematosus ... #dermatology #Differential
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... cells -> Incr local ... inflammation on skin ... Livedo Reticularis, Vasculitis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... with Systemic Lupus ... Erythematosus ( ... SLE), should have
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... vesicular eruption - Joints ... erythematosus, ... reactions, and vaso-occlusive ... , and SLE) • Urinalysis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... surfaces of the joints ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome