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diagnosis rheumatology differential management erythematosus hematology oncology signs systemic vasculitis algorithm arthropathies arthropathy autoimmune behcet classification disorders leukemia macrophage mas
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... pain • Swan neck ... : • Symptoms limited ... Chronic B-cell activation
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... with Systemic Lupus ... Erythematosus (SLE ... should have other symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs #symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... of the joints ( ... symptoms by days ... - Lupus - Leukemia ... #diagnosis #dermatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE ... Nonsurgical abdominal pain
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... • Systemic lupus ... • Fever is the main ... SJIA], systemic lupus ... erythematosus [SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... such as systemic lupus ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... vasculitis, and SLE
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... , fever, joint pain ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , and vaso-occlusive ... Presentation: Systemic Symptoms ... • Progressive symptoms ... Palpable purpura, joint
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