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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Microangiopathies #Systemic #Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... differential #diagnosis #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... • Immunologic Workup ... Positive in 60-80% of cases
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... Usual therapeutic management ... rheumatology #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... #Differential #Causes ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... (e.g. renal failure ... #Measurement #SLE ... pharmacology #levels #lupus ... #management
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
hypercarbia as causes ... be diagnostic – see ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... Classification #Classes ... differential #diagnosis #management
Can’t Intubate, Can’t Oxygenate (CICO) - Guidelines for Crises in Anaesthesia
This is the last resort when
optimal airway management ... Access – FoNA (see ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
pressure as a cause ... o Endocrine cause ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup