14 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Induction Rx: high-dose ... #CNS #neurology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Severe disease- high ... #Systemic #Lupus ... #rheumatology #management
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia ... : Drug induced SLE
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... with leukopenia, anemia ... #Diagnosis #Management
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... - Tumor lysis syndrome ... insufficiency/Failure • SLE ... differential #diagnosis #causes ... #nephrology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
0.8 Normal + High ... of High Anion Gap ... D-lactate (short bowel syndrome ... failure (uremia ... Diagnosis #Summary #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... - Tumor lysis syndrome ... insufficiency/Failure • SLE ... differential #diagnosis #causes ... #nephrology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Epidemiology 1) High ... , and possibly renal ... skin (16-32%): lupus ... Sarcoidosis #Diagnosis #Management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... and pernicious anemia ... , diaphoresis, high ... Diagnosis: • High