12 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... #Classification ... #Classes #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... nephritis, NPSLE ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... nephritis, NPSLE ... • Immunologic Workup ... life-threatening • Treatment
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... or 0.5 g/day → renal ... by 12 months Classification ... #treatment #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... permanent alopecia Differential ... APLA/LAC: • Renal ... SSA can rule in SLE
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Nephrotic ... Systemic #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... again we might see ... perfusion - shock->treatments ... before beginning treatment ... #typea #typeb #classification
Secondary Causes of Hyperlipidemia
Nunerous secondary causes of hyperlipidemia exist; screening for the presence of these underlying
mellitus, Chronic renal ... Glucocorticoid treatment ... hepatitis, Systemic lupus ... Hypothyroidism, Nephrotic ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE ... #rheumatology #classification
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #hematology #oncology