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diagnosis rheumatology management syndrome differential ana anca antibody antineutrophil antinuclear classification clinical cutaneous disease diseases erythematosus eschar mucormycosis oncology polychondritis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... ANCA-Associated Vasculitis ... vasculitis - MPO
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... : • Behçet Syndrome ... lupus erythematosus ... C-ANCA) pattern: antibodies ... , and SLE) • Urinalysis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... vasculitis) • ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Seizures • Strokes Skin ... 1, SCL-70, RNP antibodies ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Diagnosis: • Systemic ... diseases, such as SLE ... tract, and often causes ... • Behcet syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Vasculitis: • ... Adenocarcinoma Treatment
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
malnutrition, HIV, SLE ... wide excision & systemic ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
• Inner ear • Skin ... such as: • SLE ... Sarcoidosis • Behcet ... Anti-Matrilin-1 Ab ○ Antibodies ... affected tissue Treatment
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