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diagnosis rheumatology classification differential syndrome activation causes disease eularacr hematology hyperkalemia macrophage mas nephrology potassium pulmonary renal summary symptoms vasculitides
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Lupus Erythematosus ... #SLE #Systemic ... #Lupus #Erythematosus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Severe disease- high ... #Lupus #Erythematosus ... #rheumatology #management
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
IgA-associated vasculitis, Behcet ... Immune Complex: Systemic ... lupus erythematosus ... • Labs: CBC, cr ... infiltrates) → high
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Histopathologic criteria ... Syndrome #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... exacerbations: high-dose ... Syndrome #diagnosis #management ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... VASCULITIS: • Behçet ... lupus erythematosus ... purpura: strong sign ... vasculitis, and SLE
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Tubulointerstitial diseases: syßtemic ... lupus erythematosus ... (SLE), sickle cell ... Tubulointerstitial diseases: SLE ... Differential #Diagnosis #High
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