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diagnosis hematology erythematosus symptoms management oncology vasculitis algorithm behcet causes champs chronic classification cll comparison complement disease druginduced hypocomplementemia leukemia
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Lupus Erythematosus ... #SLE #hematology ... #rheumatology # ... differential #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Erythematosus #Diagnosis #autoantibodies ... #signs #symptoms ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months) and of autoantibodies ... months to years) Systemic ... • Immunologic Workup ... #table #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... (total 50, renal ... Mnemonic #diagnosis #differential ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... #Systemic #Lupus
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
macular Vasculitis) Autoantibodies ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... purpura: strong sign ... vasculitis, and SLE ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Behcet disease) Differential ... Oral aphthae : SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... ’s CLL Scoring system ... Leukemia #diagnosis #workup ... #oncology #hematology
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