7 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... diseases • In secondary ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs /
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... BUN: • Chronic renal ... Myelodisplastic syndrome ... #primary #secondary ... #dermatology #Differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... BUN: • Chronic renal ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... #Diagnosis #Management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Primary (essential ... processes: • Systemic ... • Painful or pruritic ... thrombi including retinal ... Antiphospholipid syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... other diseases • Secondary ... overlaps with RA, SLE ... ab (specific in primary ... Rheumatology #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... Types of HLH • Primary ... STX11, STXBP2 • Secondary ... Presentation • Common Signs ... #Hematology #HemeOnc