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diagnosis rheumatology systemic algorithm causes erythematosus oncology symptoms anorexianervosa chronic classification cll gap globulin leukemia lymphocytic monoclonal naildisorders normocytic paraproteinemias
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... #Differential # ... Algorithm #Causes #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia ... erythematosus #signs
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... Systemic #Secondary #dermatology ... #Differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... WBC count and differential ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... such as systemic lupus ... purpura: strong sign ... vasculitis, and SLE ... • Urinalysis (Renal
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... cancers, HCC, renal ... gastric tumors • Hematology ... #diagnosis #hematology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
fasting/weight loss RENAL ... and memory loss HEMATOLOGIC ... lymphocytosis, mild anemia ... risk of fracture DERMATOLOGIC ... pathophysiology #diagnosis #signs
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